Seroepidemiology of the Newly Found Trichodysplasia Spinulosa–Associated Polyomavirus

Seroepidemiology and primary infections of the recently detected Merkel cell polyomavirus and trichodysplasia-spinulosa associated polyomavirus

................................................................................................................... 5 LIST OF ORIGINAL PUBLICATIONS ....................................................................... 7 ABBREVIATIONS ......................................................................................................... 8 INTRODUCTION ...........................................

Seroprevalence of Trichodysplasia Spinulosa–associated Polyomavirus

We identified a new polyomavirus in skin lesions from a patient with trichodysplasia spinulosa (TS). Apart from TS being an extremely rare disease, little is known of its epidemiology. On the basis of knowledge regarding other polyomaviruses, we anticipated that infections with trichodysplasia spinulosa-associated polyomavirus (TSV) occur frequently and become symptomatic only in immunocompromi...

Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus DNAs and antibodies in blood among the elderly

BACKGROUND Merkel cell polyomavirus (MCPyV) and trichodysplasia spinulosa-associated polyomavirus (TSPyV) are recently found pathogens causing two rare skin disorders, Merkel cell carcinoma (MCC) and trichodysplasia spinulosa (TS). MCC is proportionally common in the elderly and most often is associated with immunosuppression. TS is a folliculocentric infection seen in patients in an immunocomp...

Potential Route of Transmission for Trichodysplasia Spinulosa Polyomavirus

Specific detection of trichodysplasia spinulosa–associated polyomavirus DNA in skin and renal allograft tissues in a patient with trichodysplasia spinulosa.

BACKGROUND Trichodysplasia spinulosa (TS) is a rare, disfiguring skin condition that affects immunosuppressed patients, universally involving the central face. New data point to the recently discovered TS-associated polyomavirus (TSPyV) as the causative agent. OBSERVATIONS We report a case of TS in a 48-year-old African American man after renal transplant; via polymerase chain reaction and se...